Key result
Extended antral pulmonary vein isolation combined with linear 'box lesion' and ablation of complex fragmented electrograms achieved a 56.3% success rate in maintaining sinus rhythm, compared to 15.6% with antral isolation alone.
RCT (n=95)
Open-label
Randomly assigned to ablation subgroups
No
May support adjunctive substrate ablation in AF; hypothesis-generating and requires randomized confirmation.
Сравнительный Анализ Эффективности Расширенной Радиочастотной Аблации Зон
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Bockeriа et al. (2013) conducted an RCT in Atrial fibrillation (n=95). Extended antral pulmonary vein isolation, linear 'box lesion', and ablation of complex fragmented electrograms (Subgroup C) vs. Extended antral pulmonary vein isolation alone (Subgroup A) was evaluated on Maintenance of sinus rhythm at 3 years (OR 1.6535, 95% CI 0.5502-5.0148). Extended antral pulmonary vein isolation combined with linear 'box lesion' and ablation of complex fragmented electrograms achieved a 56.3% success rate in maintaining sinus rhythm, compared to 15.6% with antral isolation alone.
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