Key result
Intradialytic hypotension-prone patients with baseline cTnI ≥0.20 ng/ml had a significantly higher risk of cardiovascular events or death at 12 months (adjusted OR 15.0, p=0.012).
Why the study?
Does intradialytic hypotension cause myocardial injury and increase the risk of cardiovascular events or death in chronic hemodialysis patients?
Population
70 chronic hemodialysis patients with no recent occurrences of acute coronary artery syndrome, divided into…
Comparison
Hypotension prone phenotype and experiencing… vs Intradialytic hypotension resistant phenotype
Design
Cohort
Follow-up
12 months
Authors
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Elevated cTnI flags high CV risk in hypotension-prone hemodialysis patients; leaves open whether preventing hypotension improves outcomes.
Cohort (n=70)
Does intradialytic hypotension cause myocardial injury and increase the risk of cardiovascular events or death in chronic hemodialysis patients?
Odds Ratio: 15
p-value: p=0.012
Symptomatic intradialytic hypotension is associated with occult myocardial injury and a significantly increased risk of cardiovascular events or death at 12 months in chronic hemodialysis patients.
Hung et al. (2004) conducted a cohort in Chronic hemodialysis (n=70). Intradialytic hypotension proneness with baseline cTnI ≥0.20 ng/ml vs. Intradialytic hypotension resistant patients was evaluated on Cardiovascular events or death (adjusted OR 15.0, p=0.012). Intradialytic hypotension-prone patients with baseline cTnI ≥0.20 ng/ml had a significantly higher risk of cardiovascular events or death at 12 months (adjusted OR 15.0, p=0.012).
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