Cardiac Arrhythmias and Silent Myocardial Ischemia During Hemodialysis
Population
38 unselected chronic renal failure (CRF) patients on regular hemodialysis
Design
Cohort
Follow-up
Approximately 48 hours
Authors
Discussion
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Member takes
Implication
Silent ischemia was associated with ventricular arrhythmias during hemodialysis; hypothesis-generating and should not yet change practice or screening in ESRD.
Structured PICO
P
Population
38 unselected chronic renal failure (CRF) patients on regular hemodialysis
I
Intervention
Continuous Holter monitoring starting 24 hours before hemodialysis, lasting through the session and continued for 20 hours thereafter
O
Outcome
Frequency, timing and severity of supraventricular and ventricular arrhythmias and silent myocardial ischemia (identified by ST-segment depression)surrogate
Silent myocardial ischemia and ventricular arrhythmias occur frequently during hemodialysis in chronic renal failure patients, suggesting a potential link to underlying coronary artery disease.
Limitations
- Lack of coronary angiography to establish a definite causal relationship
- Small sample size
Cite This Study
Narula et al. (2000) studied this question.