Key result
Hemodialysis induced silent myocardial ischemia in 22% of patients, predisposing them to significant ventricular arrhythmias independent of epicardial coronary artery disease.
Why the study?
Does silent myocardial ischemia and arrhythmias during hemodialysis correlate with epicardial coronary artery disease in patients with end-stage renal disease?
Population
23 patients with end-stage renal disease on maintenance hemodialysis.
Design
Cohort
Follow-up
48 hours
Authors
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Silent ischemia during hemodialysis may trigger arrhythmias independent of CAD; leaves open mechanisms and requires prospective validation.
Cohort (n=23)
Does silent myocardial ischemia and arrhythmias during hemodialysis correlate with epicardial coronary artery disease in patients with end-stage renal disease?
Silent myocardial ischemia during hemodialysis predisposes patients to significant ventricular arrhythmias but does not appear to be driven by epicardial coronary artery disease.
Mohiuddin et al. (2005) conducted a cohort in End-stage renal disease on maintenance hemodialysis (n=23). Hemodialysis was evaluated on Silent myocardial ischemia (SMI) during hemodialysis. Hemodialysis induced silent myocardial ischemia in 22% of patients, predisposing them to significant ventricular arrhythmias independent of epicardial coronary artery disease.
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