Key result
Elevated baseline serum cTnT >0.1 ng/ml was independently associated with age (OR 1.04), diabetes (OR 4.9), and indexed left ventricular mass (OR 1.01) in asymptomatic chronic haemodialysis patients.
Why the study?
What factors are associated with increased serum levels of cardiac troponins T and I in asymptomatic chronic haemodialysis patients?
Population
258 chronic haemodialysis patients without acute coronary symptoms, mean age 60+/-15 years, 150 men.
Design
Cross-sectional
Authors
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Should not yet change troponin thresholds in HD; leaves open prognostic utility and need for prospective validation.
Cross-Sectional (n=258)
What factors are associated with increased serum levels of cardiac troponins T and I in asymptomatic chronic haemodialysis patients?
Odds Ratio: 4.9
p-value: p=<0.005
Elevated baseline serum levels of cardiac troponins in asymptomatic chronic haemodialysis patients are associated with cardiovascular risk factors, history of ischaemic heart disease, and left ventricular hypertrophy.
Iliou et al. (2001) conducted a cross-sectional in chronic haemodialysis (n=258). Cardiovascular risk factors and left ventricular hypertrophy was evaluated on Pre-dialysis levels of cTnT >0.1 ng/ml (OR 4.9, p=<0.005). Elevated baseline serum cTnT >0.1 ng/ml was independently associated with age (OR 1.04), diabetes (OR 4.9), and indexed left ventricular mass (OR 1.01) in asymptomatic chronic haemodialysis patients.
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