Key result
Trapezoidal resection of an elongated anterior mitral leaflet combined with an edge-to-edge suture successfully resolved systolic anterior motion, left ventricular outflow tract obstruction, and mitral regurgitation in all 5 patients.
Why the study?
Does trapezoidal resection of an elongated anterior mitral leaflet with an Alfieri stitch resolve systolic anterior motion and LVOT obstruction in a patient with HOCM and mild septal hypertrophy?
Case Report (n=5)
No
Does trapezoidal resection of an elongated anterior mitral leaflet with an Alfieri stitch resolve systolic anterior motion and LVOT obstruction in a patient with HOCM and mild septal hypertrophy?
Trapezoidal resection of an elongated anterior mitral leaflet combined with an Alfieri stitch, septal myectomy, and papillary muscle relocation is a viable surgical option for HOCM patients with mild septal hypertrophy.
May warrant consideration in select hypertrophic cardiomyopathy cases; leaves open generalizability pending prospective validation.
BACKGROUND: In individuals with hypertrophic obstructive cardiomyopathy, elongated anterior mitral leaflets are commonly associated with systolic anterior motion. In patients with mild septal hypertrophy, a myectomy is considered insufficient to relieve systolic anterior motion and left ventricular outflow tract obstruction. CASE PRESENTATION: In the patient, who had relatively mild septal hypertrophy, the section of the anterior leaflet protruding into the left ventricular outflow tract was resected, concomitant with septal myectomy and the relocation of the papillary muscles. An edge-to-edge stitch was placed at the uppermost segment of the coaptation zone. Using these manoeuvres, systolic anterior motion, left ventricular outflow tract obstruction and mitral regurgitation were successfully resolved postoperatively. CONCLUSIONS: We describe a surgical technique with an edge-to-edge suture for the resection of an elongated anterior mitral leaflet. In combination with septal myectomy and relocation of the papillary muscles, this technique is a simple and viable option, especially when septal hypertrophy is not severe.
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Nakajima et al. (2020) conducted a case report in Hypertrophic obstructive cardiomyopathy with systolic anterior motion and mitral regurgitation (n=5). Trapezoidal resection of an elongated anterior mitral leaflet and Alfieri stitch (edge-to-edge suture) was evaluated on Resolution of systolic anterior motion, left ventricular outflow tract obstruction, and mitral regurgitation. Trapezoidal resection of an elongated anterior mitral leaflet combined with an edge-to-edge suture successfully resolved systolic anterior motion, left ventricular outflow tract obstruction, and mitral regurgitation in all 5 patients.
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