Key result
Exposure to PEEP and LBNP in healthy subjects showed that arteriolar rather than venous responses predominate in blood volume mobilization, with greater vascular resistance increases during LBNP.
Why the study?
How do arteriolar and venous reflex responses compare during reductions in cardiac output provoked by PEEP versus LBNP in healthy subjects?
How do arteriolar and venous reflex responses compare during reductions in cardiac output provoked by PEEP versus LBNP in healthy subjects?
p-value: p=<0.05
During reductions in cardiac output, arteriolar rather than venous responses are predominant in blood volume mobilization from skin and muscle.
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Arteriolar reflexes predominate in volume mobilization during reduced output; leaves open relevance to patients with vascular disease.
Peters et al. (1997) studied Healthy (n=5). Positive end-expiratory pressure (PEEP) and lower body negative pressure (LBNP) vs. Baseline/Control was evaluated on Forearm vascular resistance (p=<0.05). Exposure to PEEP and LBNP in healthy subjects showed that arteriolar rather than venous responses predominate in blood volume mobilization, with greater vascular resistance increases during LBNP.
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