Key result
Lack of occupational MVPA is linked to higher abdominal aortic calcification scores versus any MVPA.
Why the study?
Regular physical activity positively impacts cardiovascular risk factors, but its relationship alongside sedentary behavior with abdominal aortic calcification was not established.
Does moderate-to-vigorous physical activity and reduced sedentary behavior improve abdominal aortic calcification scores in adults aged 40 and above?
Cross-Sectional (n=2,843)
Does moderate-to-vigorous physical activity and reduced sedentary behavior improve abdominal aortic calcification scores in adults aged 40 and above?
Mean Difference: 0.46 (95% CI 0.24–0.67)
p-value: p=<0.001
Engaging in occupational moderate-to-vigorous physical activity and reducing sedentary behavior is associated with lower abdominal aortic calcification scores, particularly in older individuals and those with hypertension.
MVPA inversely associated with AAC in NHANES data; hypothesis-generating for activity interventions, prospective trials needed.
BACKGROUND AND AIMS: The increasing prevalence of metabolic and cardiovascular diseases poses a significant challenge to global healthcare systems. Regular physical activity (PA) is recognized for its positive impact on cardiovascular risk factors. This study aimed to investigate the relationship between moderate-to-vigorous physical activity (MVPA), sedentary behavior (SB), and abdominal aortic calcification (AAC) using data from the National Health and Nutrition Examination Survey (NHANES). METHODS: The study used data from NHANES participants aged 40 and above during the 2013-2014 cycle. AAC scores were assessed using the Kauppila scoring system, and MVPA and SB were self-reported. Sociodemographic variables were considered, and multivariable linear regression models were used to analyze associations between MVPA, SB, and AAC scores. Subgroup analyses were conducted based on age, sex, BMI, hypertension, and diabetes. RESULTS: The study included 2843 participants. AAC prevalence was higher in older age groups, smokers, and those with diabetes or hypertension. Lower socioeconomic status was associated with higher AAC prevalence. Individuals engaged in any level of MVPA exhibited lower AAC rates compared to inactive individuals. Not engaging in occupational MVPA (β = 0.46, 95% confidence interval = 0.24‒0.67, p < .001) and prolonged SB (β = 0.28, 95% confidence interval = 0.04‒0.52, p = .023) were associated with higher AAC scores. However, no significant associations were found for transportation and leisure time MVPA. Subgroup analysis revealed age and hypertension as effect modifiers in the MVPA-AAC relationship. CONCLUSIONS: This study highlights the potential benefits of engaging in occupational MVPA and reducing SB in mitigating AAC scores, particularly among older individuals and those with hypertension.
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Sheng et al. (2023) conducted a cross-sectional in Abdominal aortic calcification (n=2,843). Not engaging in occupational moderate-to-vigorous physical activity vs. Engaging in any occupational moderate-to-vigorous physical activity was evaluated on Abdominal aortic calcification (AAC) score (β 0.46, 95% CI 0.24-0.67, p=<0.001). Not engaging in occupational moderate-to-vigorous physical activity was significantly associated with higher abdominal aortic calcification scores (β 0.46) compared to engaging in any occupational MVPA.
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