Key result
A baroreceptor reflex sensitivity cut-off of <3 ms/mmHg identified chronic heart failure patients with significantly increased mortality risk (HR 3.19; 95% CI 1.73-5.89; P<0.001).
Why the study?
Does a baroreceptor reflex sensitivity (BRS) cut-off of <3 ms/mmHg predict increased mortality risk in chronic heart failure patients independent of age?
Population
228 chronic heart failure patients and 60 age-matched controls
Comparison
Baroreceptor reflex sensitivity (BRS) <3 ms/mmHg vs BRS ≥3 ms/mmHg
Design
Cohort
Authors
Loading...
BRS <3 ms/mmHg may stratify mortality risk in chronic HF independent of age; leaves open incremental value over standard predictors.
Observational (n=288)
Does a baroreceptor reflex sensitivity (BRS) cut-off of <3 ms/mmHg predict increased mortality risk in chronic heart failure patients independent of age?
Hazard Ratio: 3.19 (95% CI 1.73–5.89)
p-value: p=<0.001
A BRS cut-off of <3 ms/mmHg optimally identifies chronic heart failure patients at high mortality risk, independent of physiological senescence.
Gouveia et al. (2015) conducted an observational in Chronic heart failure (n=288). Baroreceptor reflex sensitivity (BRS) <3 ms/mmHg vs. BRS ≥3 ms/mmHg was evaluated on Mortality risk (HR 3.19, 95% CI 1.73-5.89, p=<0.001). A baroreceptor reflex sensitivity cut-off of <3 ms/mmHg identified chronic heart failure patients with significantly increased mortality risk (HR 3.19; 95% CI 1.73-5.89; P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: