Key result
Impella 5.5 placement in a 73-year-old male was complicated by a 1 cm laceration of the left coronary cusp resulting in severe aortic regurgitation and cardiogenic shock requiring surgical replacement.
Why the study?
Acute aortic valve insufficiency after Impella placement carries a high morbidity risk and had not previously been documented with the Impella 5.5.
Case Report (n=1)
This is the first documented case of acute aortic valve insufficiency due to leaflet disruption following Impella 5.5 placement, highlighting a severe potential complication of the device.
Answers are grounded in this paper and cite their sources.
Alerts clinicians to aortic valve injury risk after Impella 5.5 explantation; hypothesis-generating and leaves open incidence and prevention questions.
A 73-year-old male with a history of severe coronary artery disease and prior coronary artery bypass grafting (CABG) presented with chest pain and elevated troponins. His workup revealed an ejection fraction of 15%, severe native coronary disease, as well as stenosis of his bypass grafts. He underwent a high-risk redo CABG with an Impella 5.5® (Abiomed, Danvers, MA) placement. The device was removed on postoperative day eight, at which time he went into cardiogenic shock from aortic valve leaflet injury. Given that he had no calcium deposits around the aortic valve annulus and severe aortic insufficiency, a multidisciplinary heart team decided he would be best served by a surgical aortic valve replacement. He was taken back to the operating room for a surgical aortic valve and intra-aortic balloon pump. His postoperative course was complicated by pneumonia, sepsis, and renal failure requiring continuous renal replacement therapy. He was discharged to a rehabilitation facility after 42 days. The following case encompasses the high morbidity risk of acute aortic valve insufficiency after Impella placement, never before documented in an Impella 5.5.
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Ghannam et al. (2021) conducted a case report in Aortic valve leaflet disruption / Cardiogenic shock (n=1). Impella 5.5 was evaluated on Aortic valve leaflet disruption. Impella 5.5 placement in a 73-year-old male was complicated by a 1 cm laceration of the left coronary cusp resulting in severe aortic regurgitation and cardiogenic shock requiring surgical replacement.
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