Key result
Prolonged use of an Impella 5.0 device for 27 days resulted in damage to the right coronary cusp of the aortic valve, leading to severe aortic insufficiency and cardiogenic shock three years later.
Case Report (n=1)
Prolonged Impella use may cause structural damage leading to delayed, progressive aortic insufficiency and cardiogenic shock years after removal.
May cause delayed aortic insufficiency years after Impella removal; single case leaves open incidence and surveillance needs.
A 28-year-old male with atrial fibrillation and thyrotoxicosis-induced heart failure underwent multiple interventions, including extracorporeal membrane oxygenation (ECMO), multiple valve repair/replacement, and Impella placement/removal. However, after a period of three years, the patient developed progressive aortic insufficiency (AI), which was attributed to damage caused by the prolonged use of the Impella device. The discussion highlights the importance of adhering to manufacturer guidelines for device use and emphasizes the need for careful examination during placement to minimize potential complications.
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Syed et al. (2023) conducted a case report in Cardiogenic shock secondary to aortic insufficiency (n=1). Impella 5.0 LVAD was evaluated on Development of aortic insufficiency and cardiogenic shock. Prolonged use of an Impella 5.0 device for 27 days resulted in damage to the right coronary cusp of the aortic valve, leading to severe aortic insufficiency and cardiogenic shock three years later.
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