What question did this study set out to answer?

This study aims to evaluate the safety of discontinuing anticoagulation therapy in patients with intracranial hemorrhage who are at high risk for thromboembolic events.

December 1, 2000Archives of Neurology

Safety of Discontinuation of Anticoagulation in Patients With Intracranial Hemorrhage at High Thromboembolic Risk

View Full Paper

Ask AI

Bookmark

This study aims to evaluate the safety of discontinuing anticoagulation therapy in patients with intracranial hemorrhage who are at high risk for thromboembolic events.
Reviewed 141 patients with ICH and a high risk of thromboembolic events taking warfarin.
Determined the 30-day risk of ischemic stroke following warfarin discontinuation using Kaplan-Meier survival estimates.
Categorized patients based on indications for anticoagulation such as prosthetic heart valves and atrial fibrillation.
The 30-day incidence of ischemic stroke was 2.9% for prosthetic heart valve patients, 2.6% for atrial fibrillation, and 4.8% for those with previous ischemic strokes.
43% of patients experienced death during the study period.
In the cohort that restarted warfarin, there were no recurrences of intracranial hemorrhage.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Randomized trial reviews anticoagulation management in high thromboembolic risk patients with ICH, suggesting low stroke probability after warfarin cessation.

Cite This Study

Phan et al. (2000) studied this question.

synapsesocial.com/papers/6a5f2c30531077db68af397f https://doi.org/10.1001/archneur.57.12.1710

View Full Paper

Ask AI

Bookmark

Implication

Randomized trial reviews anticoagulation management in high thromboembolic risk patients with ICH, suggesting low stroke probability after warfarin cessation.

Safety of Discontinuation of Anticoagulation in Patients With Intracranial Hemorrhage at High Thromboembolic Risk

Key Points

Discussion

Implication

Cite This Study

Safety of Discontinuation of Anticoagulation in Patients With Intracranial Hemorrhage at High Thromboembolic Risk

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider