Key result
Postoperative depression, but not preoperative depression, was associated with a significantly higher rate of composite neurocognitive dysfunction (33.3% vs 14.5%) one month after cardiac surgery.
Why the study?
The authors hypothesized that depression is associated with perioperative neurocognitive dysfunction and altered quality of life one month after cardiac surgery.
Does postoperative depression increase neurocognitive dysfunction in patients undergoing cardiac surgery?
Cohort (n=320)
Yes
Does postoperative depression increase neurocognitive dysfunction in patients undergoing cardiac surgery?
Absolute Event Rate: 33.3% vs 14.5%
p-value: p=0.040
Postoperative, but not preoperative, depression is associated with neurocognitive impairment and altered quality of life one month after cardiac surgery.
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Depression symptoms may flag neurocognitive risk after cardiac surgery; leaves open whether screening alters outcomes.
Lewis et al. (2022) conducted a cohort in Cardiac surgery (n=320). Postoperative depression vs. No postoperative depression was evaluated on Composite postoperative neurocognitive dysfunction at one month (p=0.040). Postoperative depression, but not preoperative depression, was associated with a significantly higher rate of composite neurocognitive dysfunction (33.3% vs 14.5%) one month after cardiac surgery.
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