Key result
Preoperative depression was associated with a higher risk of postoperative delirium after cardiac surgery compared to no depression (34% vs 24%; OR 2.19, 95% CI 1.43-3.34).
Why the study?
Preoperative depression is linked to worse outcomes after cardiac surgery and postoperative delirium after major surgery, but its association with postoperative delirium after cardiac surgery is sparsely studied.
Does preoperative depression predict postoperative delirium in cardiac surgery patients?
Population
1133 cardiac surgery patients in Stockholm 2013-2016
Comparison
Preoperative depression vs no preoperative depression
Design
Population-based cohort study
Authors
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Supports preoperative depression screening; leaves open whether treatment reduces delirium risk.
Cohort (n=1,133)
Does preoperative depression predict postoperative delirium in cardiac surgery patients?
Odds Ratio: 2.19 (95% CI 1.43–3.34)
Absolute Event Rate: 34% vs 24%
Preoperative depression is significantly associated with a more than twofold increased risk of postoperative delirium in patients undergoing cardiac surgery.
Falk et al. (2022) conducted a cohort in Cardiac surgery (n=1,133). Preoperative depression vs. No preoperative depression was evaluated on Postoperative delirium (POD) (OR 2.19, 95% CI 1.43-3.34). Preoperative depression was associated with a higher risk of postoperative delirium after cardiac surgery compared to no depression (34% vs 24%; OR 2.19, 95% CI 1.43-3.34).
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