Key result
Preoperative depression is linked to ~131% greater risk of postoperative delirium after cardiac surgery.
Why the study?
Depression is common in patients with cardiac disease, but the importance of preoperative depression for the development of postoperative delirium following cardiac surgery is not well known.
Does preoperative depression predict postoperative delirium in patients undergoing cardiac surgery?
Comparison
Preoperative depression vs no depression
Design
Systematic review and random-effects meta-analysis of cohort studies
Authors
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May inform preoperative risk stratification for delirium after cardiac surgery; extends prior observational data via meta-analytic pooling.
Meta-Analysis (n=2,066)
Does preoperative depression predict postoperative delirium in patients undergoing cardiac surgery?
Effect estimate: OR 2.31 (95% CI 1.37-3.90)
Preoperative depression is significantly associated with a more than twofold increased risk of postoperative delirium following cardiac surgery.
Falk et al. (2020) conducted a meta-analysis in Cardiac surgery (n=2,066). Preoperative depression vs. No preoperative depression was evaluated on Postoperative delirium (OR 2.31, 95% CI 1.37-3.90). Preoperative depression was associated with a significantly increased risk of postoperative delirium following cardiac surgery (OR 2.31; 95% CI 1.37-3.90).
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