December 1, 2002Hepatology
Extrahepatic manifestations of hepatitis C among United States male veterans
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Implication
Hospital-based case-control study finds significant associations of hepatitis C with skin and renal disorders in veterans.
Key Points
- This study aims to examine the associations between hepatitis C virus (HCV) infection and various extrahepatic conditions in male veterans.
- Conducted a hospital-based case-control study using Department of Veterans Affairs databases from 1992 to 1999.
- Included 34,204 HCV-infected cases and 136,816 matched controls without HCV.
- Analyzed associations with various disorders through multivariate analyses controlling for multiple demographics.
- Significantly greater proportion of HCV-infected patients had porphyria cutanea tarda, vitiligo, lichen planus, and cryoglobulinemia.
- Increased prevalence of membranoproliferative glomerulonephritis among HCV patients, but not membranous glomerulonephritis.
- Hodgkin's and non-Hodgkin's lymphoma became significant upon age adjustment, while diabetes showed no significant association after adjustment.
Cite This Study
Hashem B. El‐Serag (2002) studied this question.