June 10, 2009Clinical Infectious Diseases
Hepatitis C Virus Infection and the Risk of Coronary Disease
Why the study?
Does Hepatitis C virus (HCV) infection increase the risk of coronary artery disease in veterans?
Population
171,665 veterans receiving care at all Veterans Affairs facilities from the Electronically Retrieved Cohort…
Comparison
Hepatitis C virus (HCV) infection vs HCV-uninfected control subjects
Design
Cohort
Authors
Discussion
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Member takes
Implication
HCV-CAD association in veterans is hypothesis-generating; leaves open whether eradication modifies events.
Structured PICO
Does Hepatitis C virus (HCV) infection increase the risk of coronary artery disease in veterans?
P
Population
171,665 veterans (82,083 HCV-infected and 89,582 HCV-uninfected) receiving care at all Veterans Affairs facilities from the Electronically Retrieved Cohort of HCV Infected Veterans.
I
Intervention
Hepatitis C virus (HCV) infection
C
Comparator
HCV-uninfected control subjects
O
Outcome
Risk of coronary artery disease (CAD)hard clinical
Hepatitis C virus infection is associated with a 25% higher risk of coronary artery disease despite a more favorable lipid profile.
Cite This Study
Butt et al. (2009) studied this question.