Key result
Hydrops (P=0.01), skin edema (P=0.01), and mild or greater mitral regurgitation (P=0.02) were significantly associated with fetal or postnatal demise in primary fetal cardiomyopathy.
Observational (n=18)
p-value: p=0.01
In primary fetal cardiomyopathy, hydrops and atrioventricular valvar regurgitation are associated with poor outcomes, whereas Tei indices have limited predictive value.
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May inform fetal counseling in rare cardiomyopathy; extends limited observational data but leaves open prospective validation.
Ezon et al. (2016) conducted an observational in Primary fetal cardiomyopathy (n=18). Hydrops, skin edema, and atrioventricular valvar regurgitation vs. Absence of these signs was evaluated on Fetal or postnatal demise (p=0.01). Hydrops (P=0.01), skin edema (P=0.01), and mild or greater mitral regurgitation (P=0.02) were significantly associated with fetal or postnatal demise in primary fetal cardiomyopathy.
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