Intravenous catheterization significantly elevated mean plasma cortisol levels during the first hour, with endocrine adaptation occurring by the second or third hour.
Observational (n=29)
Does intravenous catheterization affect plasma cortisol and growth hormone levels in volunteer subjects?
Intravenous catheterization induces a transient stress response characterized by elevated cortisol and growth hormone levels that adapt within a few hours.
Plasma cortisol and growth hormone (HGH) responses to venous catheterization were studied in 29 volunteer subjects. Repeat characterizations were performed in 18 individuals. Mean plasma cortisol levels were significantly elevated during the first hour of the initial catheterization experience. Morning and afternoon levels of cortisol were not distinguishable during the first catheterization, but PM levels were significantly lower than AM levels during the second catheterization experience. Growth hormone responses were much more variable than cortisol and were distributed logarithmically. Growth hormone responses tended to parallel cortisol responses during the first catheterization experience. Individuals who listed more symptoms in response to venipuncture and catheterization after finishing their first catheterization had significantly higher cortisol and growth hormone levels during this experience. These data suggest a definite endocrine adaptation to catheterization by the second or third hour of the experience.
Rose et al. (Sat,) conducted a observational in Volunteer subjects (n=29). Intravenous catheterization was evaluated on Plasma cortisol and growth hormone (HGH) responses. Intravenous catheterization significantly elevated mean plasma cortisol levels during the first hour, with endocrine adaptation occurring by the second or third hour.
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