Key result
Liposarcoma subtypes with greater nonlipomatous soft-tissue components on imaging tend to show less differentiation and are more aggressive histologically and clinically.
Imaging plays an important role in the diagnosis, surveillance, and response assessment of liposarcoma, with nonlipomatous components indicating more aggressive disease.
Nonlipomatous components on imaging may aid risk stratification and surveillance in liposarcoma; supports histologic correlations but leaves open prospective validation.
OBJECTIVE: The purpose of this study was to illustrate the subtypes of liposarcoma (LPS) and the significance of the nonlipomatous tumor components using multiple imaging modalities. CONCLUSION: The subtypes of LPS with greater nonlipomatous soft-tissue components on imaging studies tend to show less differentiation and are usually more aggressive both histologically and clinically. Imaging plays an important role in the diagnosis, surveillance, and response assessment of LPS.
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O’Regan et al. (2011) conducted a review in Liposarcoma. Imaging modalities was evaluated. Liposarcoma subtypes with greater nonlipomatous soft-tissue components on imaging tend to show less differentiation and are more aggressive histologically and clinically.
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