Key result
Soft tissue sarcomas are a heterogeneous group of tumors where clinical, histological, and MR imaging characteristics must be combined to narrow down the differential diagnosis and guide treatment.
This review summarizes the clinical, histological, and MR imaging features of various soft tissue sarcoma subtypes to aid in differential diagnosis.
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May aid sarcoma differential diagnosis; leaves open prospective validation of combined criteria before practice change.
Soft tissue sarcomas comprise approximately 1% of malignant tumors. There are more than 50 subtypes, but pleomorphic sarcoma, liposarcoma, leiomyosarcoma, synovial sarcoma, and malignant peripheral nerve sheath tumor account for 75%. Differentiation between these subtypes is difficult because they often present with a painless enlarging mass, and share many histological and MR imaging features. Nonetheless, subdifferentiation is important because the different subtypes have different prognoses and therapeutic strategies. In this manuscript we discuss the clinical, histological, and MR imaging features of soft tissue sarcomas according to the WHO classification. An overview is provided and differentiating features are discussed that can help to narrow down the differential diagnosis.
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Vliet et al. (2009) conducted a review in Soft tissue sarcomas. Soft tissue sarcomas are a heterogeneous group of tumors where clinical, histological, and MR imaging characteristics must be combined to narrow down the differential diagnosis and guide treatment.
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