During the transition from advanced CKD to ESRD, mean left ventricular ejection fraction significantly decreased from 53% to 50% (P=0.002), whereas left ventricular mass index remained unchanged.
Cohort (n=190)
Yes
How do left ventricular mass index and ejection fraction change during the transition from advanced CKD to ESRD?
During the transition from advanced CKD to ESRD, left ventricular ejection fraction significantly declines while left ventricular mass index remains unchanged.
Absolute Event Rate: 50% vs 53%
p-value: p=0.002
BACKGROUND AND OBJECTIVES: Abnormal left ventricular structure and function are associated with increased risk of adverse outcomes among patients with CKD and ESRD. A better understanding of changes in left ventricular mass and ejection fraction during the transition from CKD to ESRD may provide important insights to opportunities to improve cardiac outcomes. DESIGN, SETTING, PARTICIPANTS, however, ejection fraction declined during this transition period. Although left ventricular mass index is fixed by advanced stages of CKD, ejection fraction decline during more advanced stages of CKD may be an important contributor to cardiovascular disease and mortality after dialysis.
Bansal et al. (Fri,) conducted a cohort in Chronic Kidney Disease (CKD) progressing to End-Stage Renal Disease (ESRD) (n=190). Progression to End-Stage Renal Disease (ESRD) vs. Advanced Chronic Kidney Disease (CKD) baseline was evaluated on Left ventricular ejection fraction (p=0.002). During the transition from advanced CKD to ESRD, mean left ventricular ejection fraction significantly decreased from 53% to 50% (P=0.002), whereas left ventricular mass index remained unchanged.
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