Why the study?
Does chronic hemodialysis lead to progressive left-ventricular structural changes in normotensive patients with ESRD?
Population
61 normotensive patients with end-stage renal disease on chronic hemodialysis
Design
Cohort
Follow-up
2.5 years (30 months)
Authors
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Progressive septal hypertrophy and LA enlargement in normotensive ESRD on HD may reflect worsening diastolic dysfunction; hypothesis-generating and should not yet change practice.
Does chronic hemodialysis lead to progressive left-ventricular structural changes in normotensive patients with ESRD?
In normotensive patients with ESRD on chronic hemodialysis, there is progressive asymmetric septal hypertrophy and left atrial enlargement over 2.5 years, reflecting worsening diastolic dysfunction.
Hüting et al. (2008) studied this question.
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