Key result
A duration of end-stage renal disease longer than 24 months was associated with significantly higher rates of aortic valve calcification (79.1% vs 25.0%) and mitral annular calcification.
Why the study?
Does the duration of end-stage renal disease affect echocardiographic morphologic and functional cardiac changes in hemodialysis patients?
Population
44 hemodialysis patients with end-stage renal disease. Divided into ESRD duration <24 months and >24 months.
Comparison
Transthoracic echocardiography (observational) vs ESRD duration <24 months vs >24 months
Design
Cross-sectional
Authors
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No significant cardiac differences by dialysis duration; hypothesis-generating and requires prospective validation before clinical consideration.
Cross-Sectional (n=44)
Yes
Does the duration of end-stage renal disease affect echocardiographic morphologic and functional cardiac changes in hemodialysis patients?
Absolute Event Rate: 79.1% vs 25%
p-value: p=<0.05
Longer duration of end-stage renal disease in hemodialysis patients is associated with increased mitral annular and aortic valve calcification, as well as prolonged isovolumetric relaxation time indicating worsening diastolic function.
Akdemir et al. (1999) conducted a cross-sectional in End stage renal disease on hemodialysis (n=44). End-stage renal disease duration >24 months vs. End-stage renal disease duration <24 months was evaluated on Aortic valve calcification (p=<0.05). A duration of end-stage renal disease longer than 24 months was associated with significantly higher rates of aortic valve calcification (79.1% vs 25.0%) and mitral annular calcification.
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