What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: End-stage renal disease (ESRD) on maintenance hemodialysis (n=78). Primary outcome: Echocardiographic characterization of left ventricular geometry, systolic function, diastolic function, and valvular disease.

What does this research mean for the field?

Adults with end-stage renal disease on maintenance hemodialysis carry a high burden of structural and functional cardiac abnormalities, with left ventricular hypertrophy occurring in 74.4% and reduced ejection fraction in 30.8%. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To provide a comprehensive echocardiographic characterization of patients with end-stage chronic kidney disease on maintenance hemodialysis.

June 24, 2026Cardiology and Angiology An International JournalOpen Access

Cardiac Structural and Functional Alterations in End-stage Renal Disease : An Echocardiographic Study

Q: What are the key findings of this study?

Echocardiography in adults with end-stage renal disease on hemodialysis revealed left ventricular hypertrophy in 74.4% and reduced ejection fraction (<50%) in 30.8%.

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Key result

Echocardiography reveals LVH in ~74% of adults with ESRD on hemodialysis.

n=78

Population

78 consecutive adults with end stage renal disease on maintenance hemodialysis, mean age 56.3, 59.0% male…

Design

Cross-sectional

Authors

CIChadbellah ImaneCadi Ayyad University EAEl Fathi AsmaaCadi Ayyad University OMOuaziz MariamCadi Ayyad University

Discussion

Member takes

Implication

High cardiac abnormality rates in hemodialysis patients warrant caution in interpretation; leaves open prospective studies on screening and outcomes.

Key Points

To provide a comprehensive echocardiographic characterization of patients with end-stage chronic kidney disease on maintenance hemodialysis.
Single-center cross-sectional study of 78 adults with end-stage renal disease on hemodialysis.
Examinations followed the 2015 ASE/EACVI chamber quantification guidelines.
Diastolic function graded in 49 patients using the 2016 ASE/EACVI four-variable algorithm.
74.4% exhibited left ventricular hypertrophy, predominantly concentric (56.4%).
30.8% had reduced left ventricular ejection fraction (EF < 50%), with 12.8% severely reduced (EF < 35%).
77.6% had diastolic dysfunction, and 61.5% had valvular abnormalities, including moderate-to-severe aortic stenosis in 7.7%.

Study Design

Type

Cross-Sectional (n=78)

Multicenter

Structured PICO

Population

78 consecutive adults with end stage renal disease (ESRD) on maintenance hemodialysis (≥ 3 months), mean age 56.3, 59.0% male, from a single center in Marrakesh.

Outcome

Echocardiographic characterization of left ventricular (LV) geometry, systolic function, diastolic function, and the prevalence and severity of valvular diseasesurrogate

End-stage CKD patients on maintenance hemodialysis exhibit a high prevalence of severe cardiac structural and functional abnormalities, including LV hypertrophy, systolic and diastolic dysfunction, and valvular disease.

Cite This Study

Imane et al. (2026) conducted a cross-sectional in End-stage renal disease (ESRD) on maintenance hemodialysis (n=78). Echocardiography in adults with end-stage renal disease on hemodialysis revealed left ventricular hypertrophy in 74.4% and reduced ejection fraction (<50%) in 30.8%.

synapsesocial.com/papers/6a3c238ad15afadd906fa494 https://doi.org/10.9734/ca/2026/v15i3548

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Implication

High cardiac abnormality rates in hemodialysis patients warrant caution in interpretation; leaves open prospective studies on screening and outcomes.