What is the clinical evidence from this study?

Study design: Observational. Population: End stage renal disease (n=35). Intervention: Maintenance hemodialysis. Primary outcome: Echocardiographic changes (LV dilation, diastolic dysfunction, left ventricular hypertrophy, systolic dysfunction, pericardial effusion).

What question did this study set out to answer?

To evaluate echocardiographic changes in patients with end stage renal disease undergoing maintenance hemodialysis.

January 1, 2014Journal of Cardiovascular Diseases & Diagnosis

Echocardiographic Changes in Patients with ESRD on Maintenance Hemodialysis-A Single Centre Study

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Key result

In ESRD patients on maintenance hemodialysis, LV diastolic dysfunction (51.2%) and LVH (48%) were common, and LVH was significantly more prevalent in patients with Hb <10 g/dL (71.4% vs 14.3%, p=0.002).

Population

35 end stage renal disease patients on maintenance hemodialysis for at least 3 months, without obvious…

Design

Cross-sectional

Authors

SSShivendra SinghJawaharlal Nehru Medical College

Discussion

Member takes

Implication

Anemia-linked LVH prevalence in hemodialysis patients is hypothesis-generating; prospective studies needed before clinical implications.

Key Points

To evaluate echocardiographic changes in patients with end stage renal disease undergoing maintenance hemodialysis.
Included 35 ESRD patients on maintenance hemodialysis for at least 3 months.
Performed M-mode echocardiography in patients after 18 hours of dialysis without coronary artery or valvular heart disease.
Assessed correlations between hemoglobin levels, hypertension, and echocardiographic findings.
51.2% showed left ventricular dilation and diastolic dysfunction.
48% had left ventricular hypertrophy, significantly associated with hemoglobin levels (p=0.002).
28.57% presented with systolic dysfunction and 17.14% had pericardial effusion.

Study Design

Type

Observational (n=35)

Multicenter

Structured PICO

Population

35 end stage renal disease (ESRD) patients on maintenance hemodialysis for at least 3 months, without obvious clinical evidence of coronary artery disease, valvular heart disease, congenital heart disease and pericardial effusion.

Outcome

Echocardiographic changes including LV dilation, diastolic dysfunction, left ventricular hypertrophy (LVH), systolic dysfunction, pericardial effusion, regional wall motion abnormalities (RWMA), and valvular calcificationsurrogate

In ESRD patients on maintenance hemodialysis, LV diastolic dysfunction and hypertrophy are highly prevalent and correlate significantly with anemia and hypertension.

Cite This Study

Shivendra Singh (2014) conducted an observational in End stage renal disease (n=35). Maintenance hemodialysis was evaluated on Echocardiographic changes (LV dilation, diastolic dysfunction, left ventricular hypertrophy, systolic dysfunction, pericardial effusion). In ESRD patients on maintenance hemodialysis, LV diastolic dysfunction (51.2%) and LVH (48%) were common, and LVH was significantly more prevalent in patients with Hb <10 g/dL (71.4% vs 14.3%, p=0.002).

synapsesocial.com/papers/6a1649b9512cb4f7828eb23c https://doi.org/10.4172/2329-9517.1000165

Topics

Echocardiography

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