Plasma brain natriuretic peptide in takotsubo cardiomyopathy
Key result
In patients with takotsubo cardiomyopathy, mean plasma BNP was 522.5 pg/ml and significantly correlated with deltaBase, an indicator of basal hyperkinesis severity.
Why the study?
Does plasma BNP concentration correlate with the severity of basal hyperkinesis in patients with takotsubo cardiomyopathy?
Population
10 consecutive patients with takotsubo cardiomyopathy.
Design
Case_series
Follow-up
17.9 +/- 6.3 days (time to normalization)
Authors
Discussion
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Implication
Elevated BNP may support diagnosis in suspected Takotsubo; leaves open its prognostic or therapeutic utility.
Study Design
Type
Observational (n=10)
Structured PICO
Does plasma BNP concentration correlate with the severity of basal hyperkinesis in patients with takotsubo cardiomyopathy?
P
Population
10 consecutive patients with takotsubo cardiomyopathy who underwent cardiac catheterization on their first hospital day.
E
Exposure
Measurement of plasma brain natriuretic peptide (BNP) and echocardiographic deltaBase value (difference in diameter between systole and diastole at 10 mm below the aortic valve).
O
Outcome
Correlation between plasma BNP concentrations and cardiac parameters (including deltaBase value).surrogate
In patients with takotsubo cardiomyopathy, elevated plasma BNP correlates with the severity of basal hyperkinesis but is not associated with a poor prognosis.
Cite This Study
Akashi et al. (2004) conducted an observational in Takotsubo cardiomyopathy (n=10). Plasma brain natriuretic peptide (BNP) was evaluated on Correlation between BNP and deltaBase (difference in diameter between systole and diastole at 10 mm below the aortic valve). In patients with takotsubo cardiomyopathy, mean plasma BNP was 522.5 pg/ml and significantly correlated with deltaBase, an indicator of basal hyperkinesis severity.