Key result
Vector flow mapping velocity fields demonstrated excellent agreement with stereo particle image velocimetry measurements in a left ventricular phantom, with an overall vector correlation of R = 0.87.
Why the study?
Does vector flow mapping accurately estimate two-dimensional flow dynamics compared to stereo-PIV in a left ventricular phantom model?
Does vector flow mapping accurately estimate two-dimensional flow dynamics compared to stereo-PIV in a left ventricular phantom model?
Effect estimate: R = 0.87
p-value: p=<0.0001
Vector flow mapping provides fairly accurate two-dimensional flow information on cardio-hemodynamics in a phantom model, supporting its potential for clinical diagnostic use.
Validates VFM accuracy in LV phantom; leaves open in vivo and clinical validation.
BACKGROUND: The accuracy of vector flow mapping (VFM) was investigated in comparison to stereo particle image velocimetry (stereo-PIV) measurements using a left ventricular phantom. VFM is an echocardiographic approach to visualizing two-dimensional flow dynamics by estimating the azimuthal component of flow from the mass-conservation equation. VFM provides means of visualizing cardiac flow, but there has not been a study that compared the flow estimated by VFM to the flow data acquired by other methods. METHODS: A reproducible three-dimensional cardiac blood flow was created in an optically and acoustically transparent left-ventricle phantom, that allowed color-flow mapping (CFM) data and stereo-PIV to be simultaneously acquired on the same plane. A VFM algorithm was applied to the CFM data, and the resulting VFM estimation and stereo-PIV data were compared to evaluate the accuracy of VFM. RESULTS: The velocity fields acquired by VFM and stereo-PIV were in excellent agreement in terms of the principle flow features and time-course transitions of the main vortex characteristics, i.e., the overall correlation of VFM and PIV vectors was R = 0.87 (p < 0.0001). The accuracy of VFM was suggested to be influenced by both CFM signal resolution and the three-dimensional flow, which violated the algorithm's assumption of planar flow. Statistical analysis of the vectors revealed a standard deviation of discrepancy averaging at 4.5% over the CFM velocity range for one cardiac cycle, and that value fluctuated up to 10% depending on the phase of the cardiac cycle. CONCLUSIONS: VFM provided fairly accurate two-dimensional-flow information on cardio-hemodynamics. These findings on VFM accuracy provide the basis for VFM-based diagnosis.
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Asami et al. (2016) studied Cardio-hemodynamics (in vitro phantom). Vector flow mapping (VFM) vs. Stereo particle image velocimetry (stereo-PIV) was evaluated on Correlation of velocity vectors between VFM and stereo-PIV (R = 0.87, p=<0.0001). Vector flow mapping velocity fields demonstrated excellent agreement with stereo particle image velocimetry measurements in a left ventricular phantom, with an overall vector correlation of R = 0.87.
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