Key result
D-dimer levels were significantly associated with congestive heart failure severity stages, demonstrating high predictive value (AUC 0.929) and remaining an independent predictor in multivariate analysis.
Why the study?
Congestive heart failure causes significant morbidity and mortality, but research on markers of disease severity remains scarce.
Do procalcitonin and D-dimer predict the severity of congestive heart failure in CHF patients?
Cross-Sectional (n=72)
No
Do procalcitonin and D-dimer predict the severity of congestive heart failure in CHF patients?
This study evaluates the potential of procalcitonin and D-dimer as biomarkers to predict the severity of congestive heart failure.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for PCT and D-dimer in CHF severity stratification; prospective validation required before clinical adoption.
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Liyis et al. (2025) conducted a cross-sectional in Congestive Heart Failure (n=72). Procalcitonin and D-dimer vs. Lower biomarker levels / Lower NYHA stages was evaluated on Prediction of CHF severity (NYHA stages) by D-dimer (AUC 0.929, 95% CI 0.868-0.989, p=<0.001). D-dimer levels were significantly associated with congestive heart failure severity stages, demonstrating high predictive value (AUC 0.929) and remaining an independent predictor in multivariate analysis.
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