Key result
RVP linked to early-onset pacing-induced cardiomyopathy in patients with preserved LVEF and CAD.
Why the study?
There are no guideline recommendations for CRT or CSP to manage pacing-induced cardiomyopathy in patients with CAD and preserved LVEF.
Case Report (n=3)
Patients with coronary artery disease and preserved LVEF may be particularly susceptible to early-onset pacing-induced cardiomyopathy after right ventricular pacing, highlighting the potential need for conduction system pacing as a primary strategy in this population.
Pacing-induced cardiomyopathy (PICM) is defined as a drop in left ventricular ejection fraction (LVEF) in the setting of chronic, high-burden right ventricular pacing. Cardiac resynchronization therapy (CRT) and conduction system pacing (CSP) have been proposed to manage PICM. Although acute myocardial infarction has been described as a predictor of PICM, there are no guideline recommendations for CRT or CSP in patients with coronary artery disease (CAD) and preserved LVEF. In this report, we present and discuss three cases of PICM in patients with CAD and preserved LVEF.
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Gül et al. (2024) conducted a case report in Coronary artery disease with preserved left ventricular function requiring pacemaker (n=3). Right ventricular pacing was evaluated on Development of pacing-induced cardiomyopathy (reduction in LVEF). Three patients with coronary artery disease and initially preserved left ventricular function developed early-onset pacing-induced cardiomyopathy after right ventricular pacing.
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