Key result
Left bundle branch pacing dramatically reversed pacing-induced cardiomyopathy within one week in a single patient.
Why the study?
Long-term right ventricular pacing may lead to pacing-induced cardiomyopathy, for which cardiac resynchronization therapy is the most common treatment but has higher economic cost and uncertain prognosis.
Does left bundle branch pacing reverse pacing-induced cardiomyopathy?
Case Report (n=1)
Does left bundle branch pacing reverse pacing-induced cardiomyopathy?
Left bundle branch pacing may offer a rapid and effective alternative to cardiac resynchronization therapy for reversing pacing-induced cardiomyopathy.
Answers are grounded in this paper and cite their sources.
Left bundle branch pacing may rapidly reverse pacing-induced cardiomyopathy; leaves open whether it offers a viable alternative to cardiac resynchronization therapy.
Right ventricular pacing is a traditional pacing modality for patients diagnosed with atrioventricular block. However, long-term right ventricular pacing may lead to pacing-induced cardiomyopathy (PICM) characterized by ventricular systolic dyssynchrony, deteriorative left ventricular systolic function, and symptoms of heart failure. It was reported that 10%–20% of patients have developed PICM after pacemaker implantation.1–3 Cardiac resynchronization therapy is the most common treatment for PICM, although it was reported with higher economic cost and uncertain prognosis.
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Yang et al. (2021) conducted a case report in Pacing-induced cardiomyopathy (n=1). Left bundle branch pacing was evaluated on Reversal of pacing-induced cardiomyopathy. Left bundle branch pacing dramatically reversed pacing-induced cardiomyopathy within one week in a single patient.
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