Key result
Echocardiography provides profound insights into the pathophysiology of LVOT obstruction in hypertrophic cardiomyopathy, information on its clinical impact, and guidance for interventional relief.
Why the study?
What is the role of novel echocardiographic techniques in the assessment and management of dynamic LVOT obstruction in hypertrophic cardiomyopathy?
What is the role of novel echocardiographic techniques in the assessment and management of dynamic LVOT obstruction in hypertrophic cardiomyopathy?
Echocardiography, including novel modalities like vector flow mapping and contrast perfusion imaging, is essential for understanding, prognosticating, and guiding interventions for dynamic LVOT obstruction in HCM.
PURPOSE OF REVIEW: The present article reviews the recent advances in the echocardiographic assessment of left ventricular outflow tract (LVOT) obstruction in hypertrophic cardiomyopathy (HCM). In particular, it highlights the role of novel imaging techniques in promoting our understanding of the pathophysiology of obstruction and discusses the prognostic value of information obtained from exercise echocardiography and the emerging role of image-guidance technologies for interventional relief of obstruction. RECENT FINDINGS: The advent of novel echocardiography technologies, such as vector flow mapping, continues to expand our understanding of the exact mechanism of systolic anterior motion leading to dynamic LVOT obstruction by providing new insights into the interaction between pathologic mitral geometry and the left ventricular flow field. New studies provide evidence for the prognostic value of exercise echocardiography in the assessment of patients with HCM. Myocardial contrast perfusion imaging can delineate the anatomy of septal perforator arteries and identify the downstream septal perfusion bed, which is critical for safely guiding the procedure of alcohol septal ablation. SUMMARY: Echocardiography represents a versatile, continuously evolving, and easily repeatable technique, allowing truly dynamic imaging studies, and is therefore most appropriate to evaluate a dynamic disease condition such as LVOT obstruction in HCM. It provides profound insights into the pathophysiology of LVOT obstruction, information on its clinical impact, and guidance for its relief by interventional strategies.
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Popescu et al. (2015) conducted a review in Hypertrophic cardiomyopathy with left ventricular outflow tract obstruction. Echocardiography was evaluated. Echocardiography provides profound insights into the pathophysiology of LVOT obstruction in hypertrophic cardiomyopathy, information on its clinical impact, and guidance for interventional relief.
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