Key result
Hypertrophic cardiomyopathy presents a complex clinical spectrum with varied phenotypes, making diagnosis and management to prevent disease progression and sudden cardiac death challenging.
Hypertrophic cardiomyopathy presents with a complex clinical spectrum requiring individualized diagnosis and management to relieve symptoms and prevent major complications like sudden cardiac death.
Echocardiography refines HCM phenotype classification to guide symptom relief and SCD prevention; leaves open prospective validation of targeted strategies.
The clinical spectrum of hypertrophic cardiomyopathy (HCM) is complex and includes a variety of phenotypes, which leads to different types of manifestations.Although most of the patients are asymptomatic, a significant proportion of them will develop symptoms or risk of arrhythmias and sudden cardiac death (SCD).Therefore, the objectives of HCM diagnosis and management are to relieve the patients' symptoms (chest pain, heart failure, syncope, palpitations, etc.), prevent disease progression and major cardiovascular complications and SCD.The heterogeneity of HCM patterns, their symptoms and assessment is a challenge for the cardiologist.
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A 2015 study conducted a review in Hypertrophic cardiomyopathy (HCM). Hypertrophic cardiomyopathy presents a complex clinical spectrum with varied phenotypes, making diagnosis and management to prevent disease progression and sudden cardiac death challenging.
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