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July 9, 2013JAMA

Prevalence and Extent of Obstructive Coronary Artery Disease Among Patients Undergoing Elective Coronary Catheterization in New York State and Ontario

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Key result

Elective cardiac catheterization in New York State yielded a significantly lower rate of obstructive CAD compared to Ontario (30.4% vs 44.8%; P<0.001), reflecting lower pretest probability.

Why the study?

Does the probability of detecting obstructive CAD during elective cardiac catheterization differ between patients in New York State and Ontario?

Population

73,047 patients without a history of cardiac disease who underwent elective cardiac catheterization between…

Comparison

Elective cardiac catheterization in New York State vs Elective cardiac catheterization in Ontario

Design

Cohort

Follow-up

30 days

Authors

DKDennis T. KoInterventional CardiologyJTJack V. TuHeart Failure & TransplantPAPeter C. AustinHeart Failure & Transplant

Discussion

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Implication

NY's lower obstructive CAD yield may signal overutilization; leaves open optimal selection thresholds for elective catheterization in stable patients.

Study Design

Type

Observational (n=73,047)

Multicenter

Yes

Structured PICO

Does the probability of detecting obstructive CAD during elective cardiac catheterization differ between patients in New York State and Ontario?

P
Population
73,047 patients without a history of cardiac disease undergoing elective cardiac catheterization in New York State and Ontario.
E
Exposure
Elective cardiac catheterization in New York State
C
Comparator
Elective cardiac catheterization in Ontario
O
Outcome
Observed rates and predicted probabilities of obstructive CAD (defined as diameter stenosis of 50% or more in the left main coronary artery or stenosis of 70% or more in a major epicardial vessel)surrogate

Main Result

Absolute Event Rate: 30.4% vs 44.8%

p-value: p=< .001

Patients undergoing elective cardiac catheterization in New York State have a significantly lower rate of obstructive CAD compared to Ontario, likely due to a higher proportion of low-risk patients being selected for the procedure in New York.

Cite This Study

Ko et al. (2013) conducted an observational in Obstructive coronary artery disease (n=73,047). Elective cardiac catheterization in New York State vs. Elective cardiac catheterization in Ontario was evaluated on Observed rate of obstructive CAD (≥50% left main or ≥70% major epicardial stenosis) (p=< .001). Elective cardiac catheterization in New York State yielded a significantly lower rate of obstructive CAD compared to Ontario (30.4% vs 44.8%; P<0.001), reflecting lower pretest probability.

synapsesocial.com/papers/6a61151f7bdfcb316faabc5ahttps://doi.org/10.1001/jama.2013.7834

Topics

Percutaneous coronary intervention
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Use of Cardiac Procedures and Outcomes in Elderly Patients with Myocardial Infarction in the United States and Canada1997 · 307 citations
  2. 2Comparative Outcomes for Patients Who Do and Do Not Undergo Percutaneous Coronary Intervention for Stable Coronary Artery Disease in New York2012 · 77 citations
  3. 3Temporal Trends in the Use of Percutaneous Coronary Intervention and Coronary Artery Bypass Surgery in New York State and Ontario2010 · 83 citations
  4. 4Population rates of cardiac catheterization and yield of high-risk coronary artery disease2005 · 15 citations
  5. 5Low Diagnostic Yield of Elective Coronary Angiography2010 · 1,674 citations