Key result
Flat-panel-volume CT cuts calcified coronary plaque blooming artifact vs multidetector CT, halving area overestimation.
The purpose of this study was to assess the blooming artifacts in ex vivo coronary arteries at multidetector computed tomography (CT) and flat-panel-volume CT by comparing measured areas of calcified plaque with respect to the reference standard of histopathologic findings. Three ex vivo hearts were scanned with multidetector CT and flat-panel-volume CT after institutional review board approval. The area of calcified plaque was measured at histopathologic examination, multidetector CT, and flat-panel-volume CT. The plaque area was overestimated at multidetector CT by 400% (4.61/1.15) on average, and the predicted difference between the measurements was significant (3.46 mm(2), P = .018). The average overestimation of plaque area at flat-panel-volume CT was twofold (214% [2.18/1.02]), and the predicted difference was smaller (1.16 mm(2), P = .08). The extent of the blooming artifact in visualizing calcified coronary plaque is reduced by using flat-panel-volume CT.
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Sarwar et al. (2008) studied Calcified coronary plaque (n=3). Flat-panel-volume CT vs. Multidetector CT was evaluated on Difference in measured area of calcified plaque compared to histopathologic findings. Flat-panel-volume CT reduced blooming artifacts in visualizing calcified coronary plaque compared to multidetector CT, with lower average plaque area overestimation (214% vs 400%).
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