Update in Pulmonary Vascular Diseases 2014

The field of pulmonary vascular disease remains a rapidly growing area of research.In 2014, investigators discovered new genetic determinants of pulmonary hypertension (PH) risk and described novel molecular mechanisms of disease pathogenesis.New studies have provided significant insights into our understanding of disease complexity, highlighting critical roles of cellular metabolism, inflammation, and regulatory function of microRNAs that could lead to development of novel targeted therapeutics (1).Studies of the prediction of outcomes in pulmonary vascular disease and venous thromboembolism could lead to more efficient and effective management strategies.This review provides a brief summary of the many scientific accomplishments in the field of pulmonary vascular disease during the past year.