Health-related quality of life and antihypertensive medication adherence among older adults
Key result
Low physical and mental health-related quality of life scores were associated with higher odds of low antihypertensive medication adherence (OR 1.33 and 2.26, respectively).
Why the study?
Is health-related quality of life associated with antihypertensive medication adherence in older adults?
Population
2,180 older adults enrolled in a managed care organisation and treated for hypertension, mean age 75.0…
Comparison
Low health-related quality of life scores vs HRQOL scores in the top 2 tertiles
Design
Cohort
Authors
Discussion
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Member takes
Implication
Low HRQOL may flag adherence risk in older hypertensives; leaves open whether improving HRQOL boosts adherence.
Study Design
Type
Cohort (n=2,180)
Structured PICO
Is health-related quality of life associated with antihypertensive medication adherence in older adults?
P
Population
2,180 older adults treated for hypertension in a managed care organization.
E
Exposure
Low health-related quality of life (HRQOL) scores (Physical and Mental Component Summary Scores)
C
Comparator
HRQOL scores in the top 2 tertiles
O
Outcome
Antihypertensive medication adherence assessed with the eight-item Morisky Medication Adherence Scalepatient reported
Main Result
Odds Ratio: 1.33 (95% CI 1.01–1.74)
Low physical and mental health-related quality of life is significantly associated with lower adherence to antihypertensive medications in older adults.
Cite This Study
Holt et al. (2010) conducted a cohort in Hypertension (n=2,180). Low health-related quality of life (PCS and MCS scores) vs. PCS and MCS scores in the top 2 tertiles was evaluated on Low antihypertensive medication adherence (OR 1.33, 95% CI 1.01-1.74). Low physical and mental health-related quality of life scores were associated with higher odds of low antihypertensive medication adherence (OR 1.33 and 2.26, respectively).