Key result
Global chronic respiratory disease-related heart failure cases rose ~150% in older adults since 1990.
Observational
Effect estimate: EAPC 0.13 (95% CI 0-0.25)
Absolute Event Rate: 234.82% vs 208.17%
The absolute global burden of heart failure impairment secondary to chronic respiratory diseases has increased substantially among older adults from 1990 to 2021, driven largely by population aging and growth.
Signals growing HF burden from respiratory disease in older adults amid aging; extends GBD trends but leaves open causal and interventional research.
Background Chronic respiratory diseases (CRDs) and heart failure (HF) impose substantial global burdens. However, the long-term population-level burden of HF impairment under CRD cause categories remains insufficiently characterized within the GBD framework. Methods Using GBD 2021 data, we estimated the prevalence and years lived with disability (YLDs) of HF impairment under CRD cause categories among adults aged ≥55 years from 1990 to 2021. CRD cause categories included chronic obstructive pulmonary disease (COPD), interstitial lung disease and pulmonary sarcoidosis (ILD&PS), and pneumoconiosis (PC). Cases, rates, relative changes, and EAPCs were used as primary descriptive measures. Joinpoint regression, age–period–cohort analysis, inequality indices, and BAPC-based projections were used as secondary analyses to describe trend timing, age–cohort patterns, socioeconomic distribution, and historical-trend extensions through 2032. Results From 1990 to 2021, the global prevalent cases and YLDs of HF impairment under CRD cause categories increased markedly, while prevalence and YLD rates changed only modestly overall. The burden rose sharply with age, especially after age 75, and was generally higher in males. Temporal trends differed across periods. Patterns varied across SDI strata and differed by CRD subtype. Model-based extensions of historical patterns suggested that this burden pattern may remain substantial through 2032. Conclusion The burden of HF impairment under CRD cause categories showed marked population-level variation across age, sex, SDI strata, and CRD subtypes. These findings may help inform burden monitoring, public health planning, resource allocation, and long-term service planning for older adults.
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Liu et al. (2026) conducted an observational in Heart failure impairment under chronic respiratory disease cause categories. Time (1990 to 2021) vs. 1990 baseline was evaluated on Prevalence rate of HF impairment under CRD cause categories (per 100,000) (EAPC 0.13, 95% CI 0-0.25). From 1990 to 2021, global prevalent cases of heart failure impairment under chronic respiratory diseases among adults aged ≥55 years increased by approximately 150%, with a modest increase in the prevalence rate (EAPC 0.13).
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