Why the study?
How structural barriers may amplify vulnerabilities associated with age at acute myocardial infarction onset and diabetes in underserved settings remains understudied.
Does diabetes increase short-term mortality in patients with first-onset acute myocardial infarction across different age and geographic residence strata?
Population
1,591 first-onset AMI patients at the sole AMI-capable medical centre in Eastern Taiwan
Comparison
Diabetes vs no diabetes, stratified by age and urban vs rural residence
Design
16-year retrospective cohort study
Follow-up
30 days
Key result
Diabetes was associated with higher 30-day mortality after first-onset AMI, with a significantly stronger association among younger patients (aOR 3.83 vs 1.60; p-for-interaction=0.045).
Authors
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May warrant age- and residence-specific vigilance in underserved AMI care; leaves open causal pathways and intervention targets for prospective study.
Cohort (n=1,591)
No
Does diabetes increase short-term mortality in patients with first-onset acute myocardial infarction across different age and geographic residence strata?
Effect estimate: aOR 3.83 (younger) vs 1.60 (older)
p-value: p=0.045
Diabetes significantly increases short-term mortality after first-onset AMI, particularly among younger patients and those living in rural areas, highlighting a highly vulnerable subgroup in underserved regions.
Teoh et al. (2026) conducted a cohort in first-onset acute myocardial infarction (n=1,591). Diabetes vs. Non-diabetes was evaluated on overall short-term mortality (30-day mortality) (aOR 3.83 (younger) vs 1.60 (older), p=0.045). Diabetes was associated with higher 30-day mortality after first-onset AMI, with a significantly stronger association among younger patients (aOR 3.83 vs 1.60; p-for-interaction=0.045).
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