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July 23, 2026Open BiologyOpen Access

To eat or not to eat: that is the question!

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Authors

MCMichaela E. CookeRRRachel Ross

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Overview

Review synthesizes neural and physiological mechanisms shaping feeding behavior and decision-making across species, indicating pathways for understanding disorders.

Key Points

  • The review aims to synthesize current knowledge on the mechanisms influencing feeding behavior and decision-making.
  • Summarized neural and physiological mechanisms across species, focusing on rodents.
  • Outlined core circuits regulating energy balance and the role of sensory inputs in feeding.
  • Discussed the impact of reward, stress, and memory on feeding choices.
  • Identified key homeostatic circuits that control energy balance and their role in feeding behavior.
  • Highlighted that sensory signals significantly influence decision-making related to food.
  • Addressed how disruptions in these systems contribute to disorders such as obesity and anorexia nervosa.

Cite This Study

Cooke et al. (2026) studied this question.

synapsesocial.com/papers/6a61af8bfaa9903c5116a601https://doi.org/10.1098/rsob.260119
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Also Consider

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  1. 1Regulators of Appetite in Mammals – Old and New players2026
  2. 2Neural systems controlling food intake and energy balance in the modern world2003 · 37 citations
  3. 3Neural circuits regulating activity-based anorexia2026
  4. 4Editorial: Neuromodulation of mood and eating behavior2026
  5. 5Feeding-state dependent neuropeptidergic modulation of reciprocally interconnected inhibitory neurons biases sensorimotor decisions in Drosophila2024