Key result
Vasodilator antihypertensive therapy causes edema as a well-documented adverse effect driven by at least three underlying pathogenic mechanisms.
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Design
Review
Warrants edema monitoring with vasodilators; leaves open mechanism-specific prevention strategies.
ver since hydralazine, edema has been a welldocumented adverse effect of vasodilators. Pathogenesis of vasodilatory edema (VDE) is related to at least three mechanisms which include the following:
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Franz H. Messerli (2001) studied this question. Vasodilator antihypertensive therapy causes edema as a well-documented adverse effect driven by at least three underlying pathogenic mechanisms.
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