Why the study?
How should vasodilator drugs be used in the treatment of primary hypertension?
How should vasodilator drugs be used in the treatment of primary hypertension?
Vasodilators are effective for hypertension but must be combined with beta-blockers and diuretics to prevent compensatory hemodynamic and volume responses.
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May inform cautious vasodilator prescribing in hypertension; leaves open validation with contemporary agents in randomized trials.
Jan Koch‐Weser (1974) studied this question.
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