Why the study?
Does minoxidil compared to hydralazine improve blood pressure reduction when added to beta-blockers and diuretics in patients with refractory hypertension?
Does minoxidil compared to hydralazine improve blood pressure reduction when added to beta-blockers and diuretics in patients with refractory hypertension?
Minoxidil provides significantly greater blood pressure reduction than hydralazine when added to beta-blockers and diuretics in patients with refractory hypertension.
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Hypothesis-generating for minoxidil preference in refractory hypertension; leaves open need for randomized confirmation before practice change.
Gottlieb et al. (1972) studied this question.
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