Why the study?
How should vasodilator drugs be used to effectively treat primary hypertension?
Population
Patients with primary hypertension
Design
Review
Authors
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Supports triple therapy for vasodilator hypertension regimens; leaves open prospective validation in contemporary populations.
How should vasodilator drugs be used to effectively treat primary hypertension?
Vasodilator therapy for hypertension requires concomitant use of beta-blockers and diuretics to prevent counter-regulatory mechanisms and achieve hemodynamic normalization.
J. Koch-Weser (1974) studied this question.
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