Why the study?
Do vasodilators with venodilating effects provide better haemodynamic profiles for hypertensive complications associated with myocardial failure compared to pure arteriolar dilators?
Comparison
Intravenous hydralazine, intravenous diazoxide… vs Compared against each other
Design
Other
Authors
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Nitroprusside may suit hypertensive complications in heart failure better than pure arteriolar dilators; leaves open outcome trials of vasodilator classes.
Do vasodilators with venodilating effects provide better haemodynamic profiles for hypertensive complications associated with myocardial failure compared to pure arteriolar dilators?
Vasodilators that produce both venodilatation and arteriolar dilatation (e.g., nitroprusside) may be more appropriate for hypertensive complications in cardiac failure than pure arteriolar dilators.
Tarazi et al. (1976) studied this question.
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