Why the study?
Does a combination of diuretic, propranolol, and hydralazine reduce blood pressure in patients with moderate or severe essential hypertension?
Population
23 patients with moderate or severe essential hypertension.
Design
Case_series
Authors
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Hypothesis-generating for triple therapy in severe hypertension; does not support practice change without randomized confirmation.
Does a combination of diuretic, propranolol, and hydralazine reduce blood pressure in patients with moderate or severe essential hypertension?
The combination of a diuretic, propranolol, and hydralazine provides effective blood pressure reduction without significant adverse effects in patients with moderate to severe essential hypertension.
Zacest et al. (1972) studied this question.
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