Why the study?
Does combined treatment with propranolol and hydralazine reduce blood pressure and side effects in hypertensive patients compared to propranolol alone?
Population
17 hypertensive patients (5 with renovascular hypertension and 12 with essential hypertension)
Comparison
Propranolol and hydralazine vs 82 hypertensive patients who received…
Design
Cohort
Follow-up
average 28 weeks
Authors
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Combined propranolol-hydralazine may aid BP control in hypertension; leaves open superiority to monotherapy in randomized trials.
Does combined treatment with propranolol and hydralazine reduce blood pressure and side effects in hypertensive patients compared to propranolol alone?
The combined use of propranolol and hydralazine may improve blood pressure control and diminish the side-effects of each drug compared to propranolol monotherapy.
Hansson et al. (1971) studied this question.
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