Why the study?
Does oral propranolol alter hemodynamics and plasma renin activity in inpatients with untreated mild to moderate essential hypertension?
Population
20 ambulatory hospital inpatients with untreated mild to moderate essential hypertension.
Comparison
Oral propranolol therapy for one week… vs Baseline control measurements taken after 4 to 7…
Design
Cohort
Follow-up
1 week
Authors
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Associates propranolol with favorable hemodynamics in mild hypertension; leaves open mechanistic drivers of blood pressure reduction.
Does oral propranolol alter hemodynamics and plasma renin activity in inpatients with untreated mild to moderate essential hypertension?
Propranolol effectively lowers blood pressure and heart rate in essential hypertension, but its antihypertensive effect does not directly correlate with its hyporeninemic effect or the reduction in cardiac output.
Sakti Mookherjee (1977) studied this question.
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