Key result
Pharmacologic agents are an important and often unrecognized etiology of colon ischemia, and prompt recognition of this association may help reduce morbidity and mortality.
Why the study?
What pharmacologic agents are associated with the development of colon ischemia?
What pharmacologic agents are associated with the development of colon ischemia?
This review highlights pharmacologically induced alterations of colonic blood flow as an important etiology of colon ischemia to aid in prompt recognition and reduce morbidity.
Answers are grounded in this paper and cite their sources.
Alerts clinicians to medication review in colon ischemia; leaves open need for prospective confirmation.
Colon ischemia (CI) is the most common form of ischemic injury of the gastrointestinal tract. Determining the precise incidence of CI is a challenging task, because of its often brief, mild nature, and frequent spontaneous resolution, as well as its misdiagnosis as other diseases. While many underlying disease conditions may predispose patients to CI, an important and possibly overlooked etiology is that of pharmacologically induced alterations of colonic blood flow. This review details the pharmacologic agents known to be associated with CI; when possible, their mechanisms of action are described. The aim of this paper is to highlight this often unrecognized cause of CI, thereby helping physicians to be aware of the association, to recognize its occurrence promptly, and to possibly reduce morbidity and mortality.
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Hass et al. (2007) conducted a review in Colon ischemia. Pharmacologic agents was evaluated. Pharmacologic agents are an important and often unrecognized etiology of colon ischemia, and prompt recognition of this association may help reduce morbidity and mortality.
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