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November 1, 2007Tumori Journal

In a 57-year-old man with primary bilateral adrenal non-Hodgkin's lymphoma, treatment with CHOP chemotherapy and bilateral adrenalectomy was followed by death at 7 months due to disease progression.

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Population

57-year-old man with primary bilateral adrenal non-Hodgkin's lymphoma and adrenal insufficiency syndrome

Design

Case_report

Follow-up

7 months

Key result

In a 57-year-old man with primary bilateral adrenal non-Hodgkin's lymphoma, treatment with CHOP chemotherapy and bilateral adrenalectomy was followed by death at 7 months due to disease progression.

Authors

CDChiara DobrinjaGTGiuliano TrevisanGLGennaro Liguori

Discussion

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Overview

May prompt lymphoma consideration in bilateral adrenal masses with insufficiency; leaves open optimal management strategies.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
A 57-year-old man with primary bilateral adrenal non-Hodgkin's lymphoma presenting with adrenal insufficiency.
I
Intervention
Combination chemotherapy (CHOP protocol: cyclophosphamide, doxorubicin, vincristine, prednisolone) followed by bilateral adrenalectomy and cortisone acetate replacement therapy
O
Outcome
Clinical course and survivalhard clinical

Primary bilateral adrenal non-Hodgkin's lymphoma is a rare cause of adrenal insufficiency that is typically treated with chemotherapy and surgery, though prognosis remains poor.

Cite This Study

Dobrinja et al. (2007) conducted a case report in Primary bilateral adrenal non-Hodgkin's lymphoma (n=1). CHOP chemotherapy and bilateral adrenalectomy was evaluated on Clinical course and survival. In a 57-year-old man with primary bilateral adrenal non-Hodgkin's lymphoma, treatment with CHOP chemotherapy and bilateral adrenalectomy was followed by death at 7 months due to disease progression.

synapsesocial.com/papers/6a61cf27f2fc5dc74fc1f671https://doi.org/10.1177/030089160709300621
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Primary adrenal non-Hodgkin lymphoma: a case report and review of the literature2017 · 23 citations
  2. 2A Case of Primary Adrenal Lymphoma: How Do We Detect Early Progression to Adrenal Insufficiency?2024
  3. 3ADRENAL INSUFFICIENCY DETECTED BEFORE TREATMENT IN A PATIENT DIAGNOSED WITH BILATERALLY PRIMARY ADRENAL DIFFUSE LARGE B CELL LYMPHOMA:A CASE REPORT2024
  4. 4Primary Bilateral Adrenal Lymphoma Revealed by Adrenal Insufficiency: From Constitutional Symptoms to Crisis2026
  5. 5P-005 ADRENAL INVOLVEMENT IN LYMPHOMA WITH PRESERVED ENDOCRINE FUNCTION: A RARE CLINICAL CASE2026